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Further human clinical trials are needed to confirm these findings and determine the optimal dosage and duration of PQQ supplementation to reap the benefits, as previous clinical trials have reported in Table 2

Travel, workouts, and long days can increase hydration demands, and IV hydration therapy may help support replenishment as part of a recovery-focused approach

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The molecular formula and weight for nucleic acid (Supplementary Table 1) was estimated using the GC (guanine-cytosine) content of Synechococcus elongatus (60.67%) 89 for DNA and Escherichia coli for RNA (50.8%) 90

Interestingly, substituting the amino acids with alanine enhanced the peptides inhibitory ability (Table 1)