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Magnesium oxide, citrate, and sulfate tend to have the strongest laxative effect, while magnesium glycinate or microencapsulated time-release capsules may be better tolerated among people with gastrointestinal conditions

Understanding these potential mechanisms helps clinicians and patients identify strategies to minimise discomfort whilst maintaining adequate B12 intake

NNMT inhibition could have effects on methylation balance and other metabolic pathways that have not been evaluated in people

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Health conditions, such as diabetes

Physicians Committee for Responsible Medicine