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Vitamin C is believed to help regenerate glutathione after it neutralises free radicals, which is why the pairing is standard rather than incidental

Glutathione, by preventing protein oxidation, may interrupt this cycle at its earliest stage - before the autoimmune cascade is triggered or amplified

However, endogenous GLP-1 has a short half-life (of just two minutes) as it is quickly degraded primarily by an enzyme called dipeptidyl peptidase-4 (DPP-4) and renal clearance

Planta 236:765779 Pignocchi C, Kiddle G, Hernndez I, Foster SJ, Asensi A, Taybi T, Barnes J, Foyer CH (2006) Ascorbate oxidase-dependent changes in the redox state of the apoplast modulate gene transcript accumulation leading to modified hormone signaling and orchestration of defense processes in tobacco

[4] However, such studies cannot prove causation, and confounding factors (such as overall health status, healthcare engagement, or socioeconomic variables) may influence these findings

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