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Red wine with dinner is considered part of the Mediterranean diet
Additionally, GLP-1 and its sister peptide GLP-2 both play roles in maintaining intestinal barrier integrity
Cagrilintide also has one of the lowest GI odds ratios among the incretin and amylin compound class in a 2025 Bayesian network meta-analysis of multi-target obesity therapies the relevance for the stack is that adding cagrilintide to retatrutide may not compound GI burden as severely as adding a second GLP-1 agonist would
10.3390/ijms21176206 107 PollardP
In contrast, insulin can sometimes lead to weight gain due to its role in glucose storage
doi: 10.1371/journal.pone.0228556 149 AhlersLRHTrammellCECarrellGFMackinnonSTorrevillasBKChowCYet al
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