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Intramuscular (IM) B12 injections using hydroxocobalamin, the preferred licensed form in the UK are recommended when: Oral supplementation has failed to correct a documented deficiency The patient has difficulty adhering to daily oral regimens Serum B12 levels remain persistently low despite adequate oral dosing There is clinical evidence of neurological or haematological complications In line with BNF guidance, the standard IM regimen for confirmed deficiency without neurological involvement is a loading course of 1 mg hydroxocobalamin on alternate days for two weeks , followed by maintenance of 1 mg every three months
Like most things, the answer isnt cut-and-dry, but lets break it down together to understand what factors influence this timeline and what else these powerful shots can do for you
Vitamin B 12 deficiency [Internet]
Neither route is universally better the right option depends on your medical history, goals, and your providers recommendation
Supports Red Blood Cell Formation Low B12 levels can lead to anemia, making you feel weak and tired