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The reasons are multifactorial: chronic inflammation damages blood vessel walls, corticosteroid use raises cholesterol and blood pressure, lupus-specific antibodies (particularly antiphospholipid antibodies) increase clotting risk, and the metabolic disruption caused by both the disease and its treatments creates a perfect storm for atherosclerosis

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Although different reagents, such as dithiothreitol (DTT) or 2-mercaptoethanol (2-ME), are dedicated to the reduction of disulfide bonds in the new assay TCEP was applied

Finally, frequency of GSTP1 aberrant methylation in diffuse large B-cell lymphoma (DLBCL) also led to studies to validate the prognostic impact of such epigenetic alteration in these lymphomas

If a substance is not included, it generally cannot be used for routine compounding

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