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Skipping meals or eating too quickly can also blunt semaglutide's effectiveness, because the medication works by slowing stomach emptying and promoting satiety over time

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EMPA-REG Kidney Visual Abstract While empagliflozin was the first out with a CVOT, canagliflozin was the first to complete a kidney-focused flozin trial, CREDENCE, which convincingly answered any doubts from the earlier trials

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Dose adjustment or alternative treatment options can be considered