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10.1016/j.biocontrol.2011.11.002 103 MaleckK.LevineA.EulgemT.MorganA.SchmidJ.LawtonK

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The reason for this unexpected observation was that paralysis of an essential cellular defense mechanism like autophagy leads to faster accumulation of cellular waste, which triggers an enhanced rate of cell turnover through apoptosis and compensated enhanced regeneration [151]