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A 2025 review in Dermatologic Therapy concluded that glutathione is safe and effective when properly stabilized, but emphasized that topical formulations must protect it from oxidation to preserve potency ( Alzahrani, 2025 )

doi: 10.1503/cmaj.250502 150 Chvez-ManzaneraEAVera-ZertucheJMKaufer-HorwitzMVzquez-VelzquezVFlores-LzaroJRMireles-ZavalaLet al

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