New @NEJM review on GLP-1 receptor agonists just out: effects on glucose, weight, cardiovascular outcomes, #MASLD and kidney outcomes but important questions remain about durability, lean mass (muscle + bone) loss, and long-term safety
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In addition, in tissue specimens, the expression levels of FBI-1 were positively correlated with those of GPX4 (Figure 1I)
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The third path, acquiring companies that are already winning with the GLP-1 consumer, compresses the timeline and is increasingly attractive as a result, with a protein snack brand or functional beverage company commanding considerably more value in this environment than its revenue multiple would have suggested two years ago
For patients considering compounded GLP-1 options, understanding your HSA/FSA eligibility is critical to accessing affordable, personalized treatment