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Methodology and Assumptions This analysis covers the period from January 2020 through December 2025 for both patents and scientific papers

Integration with metabolic therapies: since senescent adipose tissue, liver steatosis and visceral fat contribute to metabolic decline, FOXO4-DRI might improve metabolic resilience

2025;10.1056/NEJMoa2502082

However, this heightened production may be associated with diminished functionality and efficiency, likely due to alterations in NET composition and impaired clearance mechanisms [166]

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