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long-term activation of these pathways contributes to obesity, CVD, and T2D, as reviewed in (175)

Clinical trials establishing semaglutide's weight loss benefits enrolled patients on strict weekly schedules

As of May 2026, Canada became the first G7 country to have approved generic semaglutide

More recent meta-analyses confirm that GLP-1 receptor agonists slow kidney disease progression in both diabetic and non-diabetic settings

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