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Among these compounds, erastin, sulfasalazine (SAS), RSL3, sorafenib, and FIN56 induce ferroptosis through the inhibition of the GSH/GPX4 pathway (201, 202)
doi: 10.1530/EJE-12-0167 152 VoskensCJGoldingerSMLoquaiCRobertCKaehlerKCBerkingCet al
These effects are generally not a reason to stop therapy
The third factor encompasses the selection of administration dosage, timing, and frequency, for which a substantial body of preclinical studies has currently provided evidence supporting rational optimization
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Regulacin de la expresin de genes miognicos: Estudios de laboratorio muestran un aumento de la transcripcin de factores reguladores como MyoD y miogenina durante la exposicin a MGF
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