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Glutamate is the most abundant excitatory neurotransmitter in the brain, while glutathione is a powerful antioxidant and detoxifier

Understanding the mechanism helps explain why its effects are so broad

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(72) found that anticitrullinated protein antibody (ACPA) elevated IL-1 production in RA by activating NLRP3 inflammasomes, a crucial mechanism in the pathogenesis of RA

Their technological advance shows that they can image sinusoidal blood glutathione or measure this indicator of sinusoidal plasma glutathione specifically in collected peripheral blood, which accurately reflects the amount of glutathione in liver cells. While the current study was focused on drug-induced, acute liver injury, Zheng said future work will further deepen fundamental understanding of liver-nanoparticle interactions, continue improving the tests sensitivity and accuracy, and extend the technology to help detect chronic liver injury as well

, 2022), plantmicroorganism interactions (Zhou et al