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Phase 2 trials investigated doses of 1 mg, 4 mg, 8 mg, and 12 mg administered as once-weekly subcutaneous injections

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in human subjects with acute myocardial infarction infused with native recombinant GLP-1 for 72 hours following angioplasty [66]

Investigators are studying whether the combined triple-agonist effect on appetite, energy expenditure, and hepatic lipid handling translates to reductions in liver fat content