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Standard monitoring includes: Thyroid-stimulating hormone (TSH) levels 6-8 weeks after starting or adjusting semaglutide, then every 6-12 months once stable Free T4 levels if TSH results are abnormal or symptoms suggest thyroid dysfunction More frequent monitoring with oral semaglutide due to the known pharmacokinetic interaction Additional testing if you experience symptoms of hypo- or hyperthyroidism Diabetes and Weight Parameters require ongoing assessment: Hemoglobin A1C every 3 months if therapy changes or not at goal
doi:10.7759/cureus.29458
you tear the paper
Inaba T, Saito H, Inoue T, Han I, Furukawa S, Matsuda T, Ikeda S, Muto T: Growth hormone/insulin-like growth factor 1 axis alterations contribute to disturbed protein metabolism in cirrhosis patients after hepatectomy
Weight loss from semaglutide can also increase metabolic demand, potentially requiring higher levothyroxine doses
Adequate protein helps preserve muscle mass while losing fat, leading to better body composition outcomes
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