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The dose is then increased in 2.5 mg increments every 4 weeks as tolerated, with typical maintenance doses ranging from 5 mg to 15 mg
Acknowledgements We thank Lauren Knightley, Beth Jago, Meirion Richards, and Amin Mirza of the Structural Chemistry team for their expertise and assistance, Swen Hoelder for his continuous support, Stephen Hearnshaw for his contributions to crystal optimisation, and Chris Richardson for crystallography computing support
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Die Ergebnisse stammen aus kontrollierten klinischen Studien
REDEFINE 2 ClinicalTrials.gov number, NCT05394519.) Cagrilintide-Semaglutide for Overweight and Diabetes In this phase 3a trial involving adults with obesity and diabetes, the use of cagrilintide-semaglutide resulted in a significantly lower body weight than placebo at 68 weeks.