Semaglutide & Tirzepatide and other GLP-1RAs work primarily by making you sick
EBioMedicine (2021) 65:103242
The most common are digestive issues, including: Nausea (the most common) Vomiting Changes in bowel movements (constipation or diarrhea) These usually improve over time
Injecting too close to the belly button is not ideal because the area around the navel has less fat under the skin
However, its critical to note that these findings do not imply safety in humans
When integrated with hormone optimization, nutrition, resistance training, and restorative sleep, microdosing offers a potential pathway to extend healthspan, not just lifespanallowing women to age with energy, cognitive vitality, and cardiovascular resilience.