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While in the body, it has shown the ability to regulate sleep cycles, modulate stress hormones like cortisol, and even influence pituitary hormone release (Such as LH or GH)
This is based on how well the patient responds and the severity of their deficiency
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Anyone with a known copper allergy, open wounds or broken skin at the application area, or who is pregnant or breastfeeding
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Glossary References New England Journal of Medicine
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