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Until these fundamental questions are answered, the best we can do is to continue to reduce the ratio of omega 6/omega 3 in our dietary supply of PUFA (which currently is around 10.0 compared to 12.0 just a few years ago) by increasing consumption of fish and certain plant oils, to what is considered an ideal ratio of 2.3/1.0 [37]

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The asparagine-glycine sequence forms a cyclic imide intermediate that can hydrolyze into either aspartate or iso-aspartate, fundamentally altering the peptide structure

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