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Beyond genetics, consistent medication adherence, dietary composition (especially protein and fiber intake), sleep quality, and physical activity directly correlate with weight loss magnitude

Intestinal feedback signaling and satiety

to the point that you will actually have to have medications and or bariatric surgery as an adult. Insurance coverage is an issue Without insurance, out-of-pocket costs for the drugs can run hundreds of dollars each time you fill a prescription

Follow your doctors instructions carefully to get the most benefit

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No clinical trial has ever tested this combination