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[DOI] [PMC free article] [PubMed] [Google Scholar] Stadtman ER

Additionally, metformin has been shown to be effective in reducing pregnancy-related complications in patients with PCOS, including gestational diabetes, hypertension, and preeclampsia

74 : S5462

Methylene Blue What it is: Once just a medical dye, methylene blue (MB) is now stealing the spotlight as a mitochondrial multitasker

Preparation Condition 2 (EDTA deproteinization 80 o C): Anticoagulants used during collection impacts measures of GSH Suggesting the anticoagulant used during sample collection significantly alters plasma GSH, we found lower levels of free GSH, higher levels of GSSG, and a lower ratio of free GSH to GSSG in the heparinized plasma (Preparation Condition 1) compared to the EDTA-treated plasma (Preparation Condition 2)

Given that LA is a necessary cofactor for mitochondrial -ketoacid dehydrogenases, it thus serves a critical role in mitochondrial energy metabolism