Trimethylamine N-oxide as a risk marker for ischemic stroke in patients with atrial fibrillation
The authors suggest the potential mechanisms behind these effects include L-carnitine's role in transporting fatty acids across mitochondrial membranes, enhancing beta-oxidation, reducing free fatty acid availability, and inhibiting cholesterol synthesis
Experimentally, the released active agent is optionally fitted to the Korsmeyer-Peppas equation Q/Q =kt n +b where Q is the amount of active agent released at time t, Q is the overall released amount of active agent, k is a release constant of the nth order, n is a dimensionless number related to the dissolution mechanism, and b is the axis intercept, characterizing the initial burst release mechanism wherein n=1 characterizes an erosion controlled mechanism
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New insights into the role of lipoprotein (a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease
Michigan State University, USA (1989)
