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Furthermore, the fatigue and joint pain associated with lupus flares can make regular exercise difficult

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J Appl Toxicol 2017;37:117481

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Etanercept, infliximab, and pentoxifylline: Clinical trials with etanercept, a soluble TNF- receptor immunoglobulin constant fragment fusion protein that binds and neutralizes unbound serum TNF-, were also disappointing [36,37]