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Of note, inactivation of the genes encoding DIOs in rodent models has revealed a role for DIO type 1 in iodine homeostasis and the importance of DIOs type 2 and 3 in the maturation of auditory and visual systems during fetal development (10)

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Supplementation using NO precursors such as L-arginine and beetroot extracts, as well as LC, resulted in a significant increase in circulating 25(OH)VD levels and a decrease in oxidative stress and inflammation [147]

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