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The authors thank the Cryo-Electron Microscopy Center (SUSTech), cryo-EM (KEMC) and advanced mass spectrometry facility (KMS) of the Kobilka Institute of Innovative Drug Discovery (CUHKSZ) and SUSTech Core Research Facilities for technical assistance

CF W and CF M are the relaxation correction factors for water and metabolite, respectively

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The concentration math below is provided for research completeness and parity with the rest of the calculator tool, not because injectable use is standard or recommended for this compound