Lyophilized: Store at 28 C (35.646.4 F) for short-term or 20 C (4 F) for long-term storage in dry, dark conditions [10] [11]
If switching is necessary, allow a 35 day washout period to clear residual plasma levels, then treat the new route as a fresh baseline
In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years
Vitamin B12 Shot Results While there is no downtime or recovery period associated with B12 treatments, patients can expect mild redness and bruising around their injection sites
The prevalence of cobalamin deficiency among vegetarians assessed by serum vitamin B12: a review of literature
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