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Patient stratification for determining optimal second-line and third-line therapy for type 2 diabetes: the TriMaster study

It's maybe not the best strategy

Component trials' stopping rules were defined for single-component administration and do not transfer.

Improving sleep quality and managing stress may therefore support both gut and metabolic health

Glucose homeostasis is achieved by tight regulation of insulin secretion from pancreatic cells in response to various physiological factors, including nutrients and hormonal and neuronal inputs

The GLP-1 receptor is expressed on eosinophils and neutrophils, and GLP-1RAs can reduce the expression of eosinophil surface activation markers after LPS stimulation, and reduce the production of IL-4, IL-8, and IL-13, thereby reducing the inflammatory response (Mitchell et al., 2017)