Human studies have tested astaxanthin at doses of 12 mg/day or higher without major safety concerns, though more long-term research is still needed
(PubMed) O'Gara EA, Hill DJ, Maslin DJ
2 Oxidative stress and periodontitis 2.1 Basic concepts of oxidative stress Oxidative stress refers to an imbalance between the production of reactive oxygen types (involving superoxide anions, hydrogen peroxide, etc.) and other oxidants in the cellular and extracellular environment, capable of damaging cell structures and functions ( Under normal conditions, the body regulates and neutralizes these parlous oxidants by antioxidant systems (including superoxide dismutase, glutathione peroxidase, etc.), remaining redox balance within cells ( 2.2 Relationship between oxidative stress and gingival tissue inflammation Oxidative stress is very vital in the progress of periodontitis, tightly linked with inflammation of the gingival tissues
These findings point to possible GH-mediated activity on osteoblast proliferation and differentiation
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Don Colbert, M.D