Dysfunctional TJs have been discovered in coeliac patients and potentially contributes to intestinal leakage providing an access route for gliadin to the underlying immune system in the lamina propria (Schulzke et al
, Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males, J
DesRochers TM, Kimmerling EP, Jandhyala DM et al (2015) Effects of Shiga toxin type 2 on a bioengineered three-dimensional model of human renal tissue
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The flavonoid glycoside icariin has been shown to increase the expression of Nrf2, HO-1, and GPX4, in cisplatin-treated mouse ovarian tissues and KGN cells, which may contribute to reduced OS and ferroptosis ( In vitro experiments have demonstrated that another natural flavonoid glycoside, rutin, may alleviate oxidative stress induced by ferroptosis in small white follicles of aging laying chickens via the Nrf2/HO-1 pathway (Wu Y
