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[62] these functional impairments involve impaired dopamine neurotransmission in the mesocorticolimbic projection and norepinephrine neurotransmission in the noradrenergic projections from the locus coeruleus to the prefrontal cortex

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For most healthy adults, it is reasonably well tolerated

Speaking about the recent popularity of tanmaxxing, Benditt warned that many young people underestimate the long-term dangers of ultraviolet radiation because the consequences often do not appear until years later