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Multifaceted regulation of the system A transporter Slc38a2 suggests nanoscale regulation of amino acid metabolism and cellular signaling

Modified GLP-1 Analogue Molecular Formula C 187 H 291 N 45 O 59 Molecular Weight 4113.58 g/mol Exact Mass Approximately 4111.115 Da Sequence His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH, with a hydrophilic spacer and C18 fatty di-acid attached at Lys 20 Physical Form White to off-white lyophilized powder Storage Store at -20C before reconstitution

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Additionally, blockade of GLP-1Rs in the LS with exendin-9 alone enhanced sucrose and oil intake indicating a physiologic role for these neurons to suppress food intake