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A healthcare provider may recommend slowly tapering off Ozempic before starting the new medication to minimize side effects

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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Weghuber D, Barrett T, Barrientos-Prez M, Gies I, Hesse D, Jeppesen OK, Kelly AS, Mastrandrea LD, Srrig R, Arslanian S STEP TEENS Investigators

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7.4.4 Next-generation agonists The development of dual GLP-1/GIP receptor agonists (e.g., tirzepatide) and novel blood-brain barrier-penetrant formulations may offer superior neuroprotective efficacy by more potently engaging central receptors or providing a broader spectrum of action ( 7.5 Limitations of current evidence Several limitations must be considered when interpreting the current evidence