It is designed to be more stable and usable for therapeutic purposes
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Figure 9 As deduced from computational docking the S -isomer is the preferred binding mode of the inhibitors although alternative binding conformations were suggested (Albiston et al., 2010b) However, after determination of the crystal structure of IRAP, computational docking of, e.g., 37 , 38 , and 39 into the IRAP structure demonstrated that these inhibitors all bind in the same orientation relative to the active site (Hermans et al., 2015), in contrast to conclusions drawn in previous modeling studies
Assemble all required materials: Lyophilized peptide vial Bacteriostatic water for injection (0.9% benzyl alcohol) Sterile syringes (typically 3mL for reconstitution) Alcohol prep pads Sharps disposal container Pro tip: Never use distilled water or sterile water without preservatives for multi-dose peptide vials
These form a protective membrane around the contents, allowing almost 100% bio-availability