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Understanding the established adverse effect profile provides essential context when evaluating less commonly reported symptoms, such as back pain, that patients may experience during treatment

A comprehensive review of recent clinical data highlights that while folate deficiency is common among individuals with ASD, maternal folic acid supplementation does not correlate with higher risk of the disorder, indeed folate therapy has been associated with improved neurodevelopmental outcomes (Vasconcelos et al., 2025)

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La recomendacin en adultos es de 900 microgramos al da