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Your body releases it from extracellular matrix proteins whenever tissue damage occurs, essentially functioning as a biological signal that activates repair mechanisms

47 Taken together, these data suggest the reduced GSH/GSSG antioxidant capacity is insufficient to counter excessive OH production, and that unopposed OH can reach the nucleus to create the oxidative DNA adduct, 8-oxo-dG

Glutathione can regenerate these antioxidants by donating electrons, allowing them to continue their protective role in the body

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For most oral supplements, 2,000 mg per day is considered the upper safe limit for short-term use