Despite the importance of TJs in cellcell adhesion, it is the more basal desmosome structures that are primarily responsible for the mechanical strength of the intestinal epithelium by acting as spot-welds that clutch cells together (Roxas and Viswanathan 2018)
Other unofficial FOXO4-DRI dosages I have seen recommended include: 300 mcg/kg injected intravenously every other day over 5 days (Source) 60 mg injected subcutaneously twice a week (Source) If I ever do choose to use this peptide, I would go with Bens protocol as a subcutaneous injection is purported to last longer due to slower absorption
Mechanisms include: UVB: Direct DNA damage (CPDs) that impair fibroblast function UVA: Oxidative stress that degrades collagen and elastin Anatomical reflection: Light bounces into the orbital area, increasing cumulative exposure This is why we stress sunscreen around the eye area is not optional
Serious adverse events are not reported in the literature
GHK-Cu Acetate Suggested directions GHK-Cu Troche Dissolve one troche sublingually or between gum and cheek one time daily This compounded medication is only available when the commercially available product is unavailable or when a prescriber determines that there is a clinically significant difference for the patient
3 The second determinant of blood uric acid levels is the rate of uric acid excretion from the kidneys
