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In addition, GLP-1 exhibits a glucagonostatic effect through a glucose-dependent inhibition of glucagon release (3) which, compared to GLP-1-induced insulin secretion, may be equally important for the overall plasma glucose-lowering effect of GLP-1 (4)

Gallbladder Issues: A small percentage of patients may develop gallstones or gallbladder inflammation

Steady weight change : One to two pounds per week, or measurable changes in waist circumference

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(A) The results of transcript-level prediction analysis

Due to this extended activity, side effects can last several days, which is why these medications are typically started at low doses and gradually titrated to the desired level