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Incorporate EMR alerts for missed refills or lab values

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Patients experiencing severe dehydration symptoms (dizziness, decreased urination, confusion) or signs of significant electrolyte disturbance (irregular heartbeat, severe fatigue, numbness or tingling) should seek prompt medical care

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Although this impact in normal growth, strong evidence has been provided that IGF-1R is not an absolute requirement for normal growth, only partially (Baserga, 1999)