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[10] In the research literature, MGF has been proposed to act early after muscle damage to mobilize satellite cells, whereas the systemic IGF-1 isoform (IGF-1Ea) and analogs like LR3 are framed as driving the later proliferative and anabolic phases though these distinctions come largely from cell and animal work and remain incompletely resolved

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10.1016/j.cell.2021.06.019 113 WeiH.ZhaoM.HuangM.GaoJ.YuT.et al (2022)

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Varga, Z

Consumption of drugs or alcohol can alter dopamine signaling in mesolimbic reward pathways, which helps reinforce substance-seeking behavior