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In clinical practice, the high-confidence indications are narrower and more specific than the internet suggests

In Canada and most of the European Union, its not approved for medical or cosmetic use and is considered an unregulated compound (Health Canada advisory listing AOD9604 as unauthorized)

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B12 replacement produces the clearest results in people whose levels are low

Therefore, if someone does not have these IFAB antibodies, it does not rule out PA