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they can be catastrophic

Decreased tonic inhibition in cerebellar granule cells causes motor dysfunction in a mouse model of Angelman syndrome

5.4 Combination of systemic therapy and immunotherapy in HCC Before ICI immunotherapy had modified the management of HCC in the past few years, around 50% of patients with HCC received systemic therapies, generally, sorafenib or lenvatinib in the first line, followed by regorafenib, cabozantinib or ramucirumab as the second

Weitzberg, E., Hezel, M., & Lundberg, J

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