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The mechanism itself is plausible: copper acts as a cofactor for enzymes involved in skin's repair and collagen processes, which is partly why GHK-Cu has drawn so much interest

Kashin-Beck disease Kashin-Beck disease (KBD) is an endemic condition that affects an estimated 2.5 million people in Tibet, northern and central China, North Korea, and southeastern Siberia, a region of Russia (58)

doi: 10.1074/jbc.M101148200

doi: 10.2174/138945006777435290 93 FrstermannUSessaWC

Glutathione is one of the powerful antioxidants found in plants and animals

Cells were cultured for 4 days with or without hemin (1 M) and pyruvate (1 mM)