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Sugino N, Karube-Harada A, Taketani T, Sakata A, Nakamura Y

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Hchsmann C, Dorling JL, Martin CK, Earnest CP, Church TS

This leads to: More glucose remaining in circulation after meals More insulin release to compensate More energy stored as fat initially subcutaneous, but eventually as visceral fat As VAT accumulates, it drives inflammation, insulin resistance, and metabolic dysfunction creating a vicious cycle

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