Insulin deficiency or resistance interferes with glucose utilization, limiting energy availability for sperm motility ( 3 Mechanisms of spermatogenesis disorders 3.1 Mitochondria and oxidative stress Mitochondria play a pivotal role in regulating sperm function by modulating essential processes, including metabolism, signal transduction, energy production, and responses to oxidative stress
Protein Prioritization Maintaining adequate protein intake prevents muscle loss during rapid weight reduction
Tirzepatide, a dual GIP/GLP-1 receptor agonist, showed even more favorable body composition outcomes in trial data, with some participants losing up to 22% body weight while maintaining or gaining lean muscle in certain compartments
Some of the GLP-1 medications available in the market include Dulaglutide (Trulicity), Exenatide extended-release (Bydureon BCise), Exenatide (Byetta), Semaglutide (Ozempic), and Liraglutide (Victoza, Saxenda)
Wang Y, Wu W, Mao D, Teh C, Wang B, Liu B