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Formulation alternatives may provide relief: Different tablet formulations with alternative inactive ingredients may be better tolerated Liquid preparations can be easier to tolerate and allow flexible dosing Intramuscular injections completely avoid the gastrointestinal tract and are particularly useful for those with absorption issues (such as pernicious anaemia or malabsorption) or persistent oral intolerance Review inactive ingredients: Examine the supplement label for potential irritants or allergens

Am J Chin Med 47:477494 Hu S, Nawaratna G, Long BD et al (2017) The hydroxyprolineglycine pathway for glycine synthesis in neonatal pigs

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