Perks, P., Huynh, E., Kaluza, K., & Boullata, J
However, the lack of human safety data, economic disincentives, and doping controversies underscore the challenges ahead
It's an injectable FDA-approved medication, prescribed by doctors and popular for off-label weight loss benefits
Secombe DW, James L, Hahn P, Jones E
Furthermore, reproducibility of clinical trials is limited as they differ in design (small numbers of participants and heterogeneous groups, short duration), do not capture participants health status, age, diet and baseline microbiota, focus on short-term symptom improvement and report symptom relief without investigating mechanisms, e.g., metabolomics and immunomodulation
On average people lose significant weight in 3-6 months