These medications work by mimicking a natural hormone that slows gastric emptying and signals fullness to the brain
Although the pancreas is the main target organ for the action of GLP-1RAs in diabetes treatment, it turns out they do SO much more
Retatrutide is a triple receptor agonist (GLP-1, GIP, and glucagon) that produced 24.2% average weight loss over 48 weeks in Phase 2 trials
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Semaglutide is administered subcutaneously (under the skin, not into muscle) once weekly, typically in the abdomen, thigh, or upper arm
GLP-1RAs, including semaglutide, liraglutide, and tirzepatide, are currently FDA approved for the treatment of obesity in patients with a body mass index (BMI) greater than or equal to 30 or a BMI greater than or equal to 27 in the setting of an obesity-related comorbidity, including asthma