The group of metabolic disorders known as DM is characterized by hyperglycaemia, dyslipidemia, and insulin resistance
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This further activates your glial cells and a vicious cycle is set in motion
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The intrinsic pathway is triggered by disruptions in the cellular microenvironment, demarcated by mitochondrial outer membrance permeabilization, and precipitated mainly by caspases 3 (Sanz et al., 2023)