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Vitamin B12 absorption from food requires several steps: intrinsic factor secretion from gastric parietal cells, acid-dependent release of B12 from food proteins, and physical contact time in the ileum where transcobalamin receptors capture the B12-intrinsic factor complex

The relative abundance of Erysipelatoclostridium was increased in vehicle-treated mice that underwent the WD to LD switch (WD/LD-V) relative to the two control groups (LD/LD-V and WD/WD-V) but was not increased in 5A-1MQ-treated mice that underwent the same diet switch (WD/LD-T)

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Each vial is sealed and prepared in controlled environments designed to maintain sterility and product integrity